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Reduced glutathione (GSH) is the biologically active form used by the body

Thiols Antioxidant capacity Thiols, molecules that contain a sulfhydyl (SH) side chain group, act as antioxidants, stabilizing free radicals by accepting their unpaired electron

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To achieve antibody functionalization, we applied a sequential labelling strategy, including reduction with TCEP, and then the alkynes ( 19-22 ) were covalently attached to trastuzumab, allowing subsequent click chemistry for conjugation with TAMRA-PEG 3 -azide (Fig